Transforming Obesity Treatment with GLP-1s for Older Adults
利用 GLP-1 改變老年人的肥胖治療
A recent survey conducted by Gallup reported that perceived effectiveness of weight loss injections are relatively consistent among younger and middle-aged adults, with 70% of those aged 18 to 49 and 67% of those aged 50 to 64 reporting them as effective or extremely effective. Among adults aged 65 and older, however, reported effectiveness is much lower, at 48%.
蓋洛普最近進行的一項調查報告顯示,年輕人和中年人對減重註射的有效性認知相對一致,18 至49 歲人群中70% 和50 至64 歲人群中67% 表示減重註射有效或極度有效。然而,在 65 歲及以上的成年人中,報告的有效性要低得多,為 48%。
Older adults often face more health issues or comorbidities, which can make it challenging for them to lose weight and adhere consistently to their treatment plans. Additionally, healthcare providers may encounter greater difficulties in keeping older adults engaged and motivated throughout their weight loss journey.
老年人經常面臨更多的健康問題或合併症,這使得他們減肥和堅持治療計劃變得困難。此外,醫療保健提供者在讓老年人在整個減肥過程中保持參與和積極性方面可能會遇到更大的困難。
This age-related disparity points to the need for more tailored treatment plans, closer monitoring of the patient’s day to day health metrics, and additional research to better understand the overall effectiveness of GLP-1 medication to treat obesity in older adults
這種與年齡相關的差異表明需要更量身定制的治療計劃、更密切地監測患者的日常健康指標以及進行額外的研究以更好地了解 GLP-1 藥物治療老年人肥胖的整體有效性
Mitigating medication risk with remote health tech
透過遠距醫療技術降低用藥風險
One approach to addressing these challenges is the integration of digital care solutions, which can offer greater protection for older patients. By utilizing remote monitoring technologies, healthcare providers can track vital health metrics in real-time, allowing for prompt adjustments to treatment plans as needed. These tools can also facilitate regular communication between patients and providers, ensuring that any concerns or side effects are quickly addressed, thus enhancing the overall effectiveness and safety of the treatment.
應對這些挑戰的一種方法是整合數位護理解決方案,這可以為老年患者提供更大的保護。透過利用遠端監控技術,醫療保健提供者可以即時追蹤重要的健康指標,從而根據需要及時調整治療計劃。這些工具還可以促進患者和提供者之間的定期溝通,確保快速解決任何問題或副作用,從而提高治療的整體有效性和安全性。
With connected health devices that collect patient-generated data on a daily basis, care teams can have more insight into health risks that older patients are more susceptible to when taking GLP-1s:
借助每天收集患者產生數據的互聯健康設備,護理團隊可以更深入地了解老年患者在服用 GLP-1 時更容易遭受的健康風險:
- Sarcopenia: About a quarter of GLP-1 agonist weight loss results from the loss of muscle and bone, both of which are necessary to protect us as we get older. Although some muscle loss is a natural part of aging, it accelerates while on GLP-1s. Weakened muscles can make everyday activities difficult, and can lead to falls or other injuries. Low muscle mass is also associated with poor health outcomes — researchers found that individuals with diabetes and low muscle mass have a higher risk of mortality from cardiovascular disease.
肌少症:大約四分之一的 GLP-1 激動劑體重減輕是由於肌肉和骨骼的損失造成的,隨著年齡的增長,肌肉和骨骼對於保護我們是必要的。雖然有些肌肉流失是老化的自然現象,但服用 GLP-1 時肌肉流失會加速。肌肉無力會使日常活動變得困難,並可能導致跌倒或其他傷害。低肌肉質量也與不良的健康結果有關——研究人員發現,患有糖尿病和低肌肉質量的人死於心血管疾病的風險更高。 - Malnutrition: Although suppression of appetite is a key mechanism of GLP-1 medications, too much appetite control can be dangerous, particularly in older adults who are more prone to having reduced food intake. Studies have found diminished appetite is a common problem for older adults — both those living at home and at care facilities. Early insight into a patient’s weight and body composition can help care teams intervene earlier to promote better appetite and food intake. Low muscle mass further compounds the risk of malnutrition. A study led by the Center for Translational Research in Aging & Longevity at Texas A&M University found that current care approaches for malnutrition often don’t account for the importance of muscle mass restoration. Researchers recognized the challenge of measuring body composition in clinical practice, noting “the need to raise awareness of the importance of screening and managing ‘at risk’ patients so it becomes routine is imperative for change to occur.”
營養不良:雖然抑制食慾是 GLP-1 藥物的關鍵機制,但過多的食慾控制可能是危險的,特別是對於更容易減少食物攝取的老年人。研究發現,食慾減退是老年人的常見問題——無論是住在家裡還是住在護理機構的老年人。及早了解患者的體重和身體組成可以幫助護理團隊儘早進行幹預,以促進更好的食慾和食物攝取。肌肉質量低進一步加劇了營養不良的風險。德州農工大學老化與長壽轉化研究中心領導的一項研究發現,目前針對營養不良的照護方法通常沒有考慮到肌肉質量恢復的重要性。研究人員認識到在臨床實踐中測量身體組成的挑戰,並指出“需要提高對篩檢和管理‘高風險’患者重要性的認識,使其成為常規,這對於發生改變至關重要。” - Gastrointestinal side effects: Severe gastrointestinal side effects from these medications can result in dehydration, which may increase the likelihood of falls. The most commonly reported side effects include gastrointestinal issues such as vomiting and nausea. When dehydration occurs, individuals are more prone to dizziness or fainting, raising the risk of falling. For older adults a fall could be the start of serious health issues and can even lead to a long-term disability. It is essential to ensure that older adults taking weight loss medications can monitor their hydration levels on a daily basis.
胃腸道副作用:這些藥物引起的嚴重胃腸道副作用可能導致脫水,從而增加跌倒的可能性。最常見的副作用包括嘔吐和噁心等胃腸道問題。當脫水發生時,個人更容易頭暈或昏厥,從而增加跌倒的風險。對於老年人來說,跌倒可能是嚴重健康問題的開始,甚至可能導致長期殘疾。確保服用減肥藥物的長者能夠每天監測自己的水分水平至關重要。
Daily monitoring of lean mass, water percentage and bones mass
每日監測瘦體重、水分百分比和骨量
With the Withings Body Pro 2 cellular scale, patients can weigh in each day at home and their body composition information will transmit to their care team automatically. This scale was designed for maximum ease of use, making it ideal for older patients who may not be tech savvy — there’s no technical setup required, and patients can use it even if they don’t have a cell phone or internet service.
借助 Withings Body Pro 2 細胞秤,患者可以每天在家中稱重,他們的身體組成資訊將自動傳輸給他們的護理團隊。該量表的設計最大限度地提高了易用性,非常適合不懂技術的老年患者——無需任何技術設置,即使患者沒有手機或網路服務也可以使用它。
Daily lean mass, fat mass, water percentage and bone mass metrics provide early insight into which patients are struggling with muscle loss or malnutrition. With this data teams can more quickly identify problems and reach out to those in need. For instance, encouraging patients to increase protein in their diet, drink more water, and do light strength training may help stave off serious health issues.
每日瘦體重、脂肪量、水分百分比和骨量指標可以幫助您及早了解哪些患者正在遭受肌肉損失或營養不良的困擾。借助這些數據,團隊可以更快地識別問題並聯繫有需要的人。例如,鼓勵患者增加飲食中的蛋白質、多喝水和進行輕度肌力訓練可能有助於避免嚴重的健康問題。
Motivating and connecting
激勵和聯繫
According to the Pew Research Center, about 27 percent of American seniors live alone. This puts them at higher risk of social isolation, which can affect their well-being and increase their risk of health problems.
根據皮尤研究中心的數據,大約 27% 的美國老年人獨居。這使他們面臨更高的社會孤立風險,從而影響他們的福祉並增加他們出現健康問題的風險。
Beyond measuring body composition, the Body Pro 2 scale can deliver motivational messages to patients automatically. These messages might offer encouragement to keep walking regularly, take their readings more consistently, remind them of upcoming appointments or congratulate them for reaching a personal health goal.
除了測量身體組成之外,Body Pro 2 體重計還可以自動向患者傳遞激勵訊息。這些訊息可能會鼓勵他們繼續定期行走、更一致地進行閱讀、提醒他們即將到來的約會或祝賀他們實現個人健康目標。
Prioritizing a personalized approach
優先考慮個人化方法
Safely prescribing GLP-1 medications for older adults requires a multifaceted approach that combines the integration of connected health devices, closer monitoring of patient body composition, and consistent patient motivation.
為老年人安全地開出 GLP-1 藥物需要採取多方面的方法,將互聯健康設備的整合、對患者身體組成的密切監測以及一致的患者動機結合起來。
These technologies not only enhance the safety and effectiveness of weight loss treatments but also provide motivational support to help older patients stay engaged and connected. By addressing the unique challenges faced by older adults, healthcare providers improve the success of their program.
這些技術不僅提高了減重治療的安全性和有效性,還提供了激勵支持,幫助老年患者保持參與和聯繫。透過解決老年人面臨的獨特挑戰,醫療保健提供者可以提高其計劃的成功率。
Disclaimer: The information provided in this article is informational and for content marketing purposes only. It should not be construed as medical advice. The content herein is not intended to replace professional medical consultation, diagnosis, or treatment. We expressly recommend that individuals seek advice from a qualified healthcare professional before considering the use of GLP-1 medications for the treatment of obesity or any other condition.
免責聲明:本文提供的資訊僅供參考,僅供內容行銷之用。它不應被視為醫療建議。本文內容無意取代專業醫療諮詢、診斷或治療。我們明確建議個人在考慮使用 GLP-1 藥物治療肥胖或任何其他病症之前先諮詢合格的醫療保健專業人員的建議。